Case1
the Gynecological field
| Case provider |
Shuhei ISHII |
Clinical Pathology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research |
Case explanation
A Chinese woman in her 30’s (gravida 0, para 0)
Chief complaint: Abnormal vaginal bleeding
Medical history: Appendicitis
She was aware of abnormal vaginal bleeding, and was referred to our hospital.
MRI revealed masses (69x61x27mm) growing externally from the posterior lip of the uterovaginal region. Then, a cytological examination of the cervix was performed.
Cytological photo
（refer to the slide data below）
Diagnostic options
- Follicular cervicitis
- High-grade squamous intraepithelial lesion
- Adenocarcinoma, HPV-associated
- Malignant lymphoma
- Small cell neuroendocrine carcinoma
Case2
the Pulmonology field
| Case provider |
JU YOUNG LEE |
CMIAC, Department of Pathology KYUNG HEE UNIVERSITY MEDICAL CENTER, Korea |
Case explanation
M/69, Smoking for 43 years
Low‐dose computed tomography(LDCT) screening test:
→Abnormal
About 1.6cm sized solid nodule at Right Upper Lobe.
→R/O lung cancer.
R/O benign nodule such as tuberculoma, organizing pneumonia.
The submitted slide is a bronchial washing cytology
Cytological photo
（refer to the slide data below）
Diagnostic options
- Squamous cell carcinoma
- Carcinoid Tumor
- Small cell carcinoma
- Large cell neuroendocrine carcinoma
- Rhabdomyosarcoma
Case3
the Body fluid field
| Case provider |
Yu-Lin Ko |
Division of Pathology, Fu Jen, Catholic University Hospital, R.O.C. Taiwan |
Case explanation
A 45-year-old woman with regular menstruation
Pelvic pain, menorrhagia, and abdominal bloating
Massive hemorrhagic ascites, r/o malignant ascities
Type of specimen：Fluid cytology plus cell block
Cytological photo
（refer to the slide data below）
Diagnostic options
- Negative
- Mesothelial proliferations
- Adenocarcinoma
- Small cell carcinoma
- Lymphoma or other hematopoietic tumor
Case4
the Urological cytology
| Case provider |
Yuki TERAMOTO |
Department of Diagnostic Pathology, Kyoto University Hospital |
Case explanation
70-year-old female
The patient has been experiencing itching in the genital area for the past six months, and white patches are observed on the inner sides of both labia majora.
Fungal hyphae were detected with KOH, and topical therapy was administered but showed limited improvement. She visited our hospital for further evaluation.
Urine cytology was performed for screening.
Cytological photo
（refer to the slide data below）
Diagnostic options
- Benign
- Low-grade urothelial carcinoma
- High-grade urothelial carcinoma
- Squamous cell carcinoma
- Other malignancy
